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and pH — Orin’s Theory
been in the psoriasis battle for half my life, 34 now. I've been
relatively fortunate in that I was in my late teens before there were any
spots that didn’t go away in a few weeks and the onset was gradual,
giving me time to adapt to life as a flaker instead of being shocked by
getting it all at once.
I'm now at about 30% and getting slowly but steadily worse.
been devouring every bit of information I can get hold of to find the
common denominator to all the symptoms. I will list the problems I've had
that I have felt contributed to or are related to my P:
Chronic strep throat just before thanksgiving each year until the
age of about 14; allergies, i.e. sinus problems and hives from grass —
especially Johnson grass — from age 14 until about 20; since I
was 19, P spots that have appeared no longer go away.
I tried one prescription — betamethasone dipropionate (Diprolene)
— when I was about 25 years old.
It completely cleared me in days.
It worked great until I started puking.
It took me some time to realize the steroid was causing it.
When I ran out of the Diprolene and asked for more
the derm said “No more.”
I read literature on corticosteroids and the potential side effects!
My opinion is that using such wicked medicines to treat P is like
burning down the house to get rid of a fly.
inspired me to write is that after reading numerous posts I have seen that
others have noted some of the things that I have. Anecdotal evidence: P
will first occur or get worse or get better on moving to a different
locale. Beginning an exercise regimen can begin or make P worse.
Changing diet can change P. Tends to be seasonal. Stress, whether
physical or emotional, makes it worse. Pregnancy has been noted to cause
remission of P. Defects in [amounts of] calcium, zinc/copper ratio, lack
of absorption of some fat soluble vitamins — all these are implicated
according to my studies.
might have found the common denominator.
facts: Stress pushes the body toward acid. The most active mineral in the
body is calcium. If it is not being used in the body properly then all of
the other vitamins and minerals I mentioned can't be used properly.
And for calcium to work properly the pH of the body must be
maintained within very narrow limits.
The most significant means for the body to control pH level is by
breathing. Hyper-ventilation increases pH meaning more alkalinity.
Hypo-ventilation decreases pH meaning more acidity. Secondarily the
kidneys can respond to a pH out of range.
relation between pH and psoriatic symptoms:
When calcium isn't being used right due to pH out of range ever so
slightly the collagen/elastin ratio of normal skin isn't achieved.
The result is stiff, non-pliable skin that is inclined to break
instead of stretching then returning to shape. In the case of joints,
stiff cartilage breaks instead of being a good slick cushiony barrier and
fingernails don't know whether they are supposed to be nail, soft skin or
suggest a condition gets set up in the body where the pH is bouncing from
too low to too high.
This can be observed by the apparent cyclic nature of plaque
Inspect a lesion, it grows like mad for a time, then stops and is
might be a good moment to mention the pregnant lady whose psoriasis
disappears until post-partum. Her system, according to Lange
Current Diagnosis and Treatment 34th edition, "The physiologic
state of pregnancy is chronic respiratory alkalosis..." in chapter 9,
section on acid-base disorders.
for new exercise routine, moving to different locale, and seasonal
these all have to do with the amount and/or quality of water
consumed. What is the pH of water input to the body?
Need I state the effect of diet?
I might mention at this point that foods that are acid before
consumption may end up being an alkaline when processed in the body and
And it may be that the pH is low at one time of day and high at
am trying to locate some very accurate pH test strips to monitor my own
body pH in both saliva and urine to try to verify this theory. I would
like to hear anyone’s thoughts on this and I will get back in a couple
weeks to inform of my results with pH monitoring.
for the day we can all stand with our heads held high in our black suits,
or birthday suits!
As theories go, Orin, yours tastes meaty.
I’m eager to learn what your pH measurements look like.
I did a quick search of “pH” in the psoriasis
news group archives and found a number of references, but nothing so
focused as your theory.
aside about pH and pregnancy was VERY interesting.
As you probably know, the discussion about pregnancy and P has run
pretty much unabated here at FlakeHQ for 5 years.
You’ll get at least 30 hits on the word “pregnancy” through
We’ve naturally pointed our noses in the direction of hormones. Maybe
“chronic respiratory alkalosis” offers a different avenue to
don’t know enough about the relationship between pH and human biology to
offer any respectable challenges to your theory.
I do remember from chemistry that pH — degree of alkalinity or
acidity — is a spectrum upon which much can be measured, and I think I
usually see it as a measuring device in concert with other
measuring devices (at least, I think I do).
If my recollection is sound (getting more ify every year),
this would indicate pH is a general measurement rather than a specific
In other words, it might help define a quality of something but, in
and of itself, it cannot define anything specifically.
Rather like body temperature — 104 degrees indicates fever in an
adult human, but the measurement may not define its cause — wherefrom
We may find that P flares can be associated with a particular pH or
— as you suggest, I think — a particular change in pH — but
will that point to a therapy?
That’s where I start drawing blanks, because I don’t know
enough about pH.
you must keep us apprized as you pursue this.
In the meantime, I hope some FlakeHQ readers more versed in this
biochemistry will add their two cents, as you requested.