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and P Study
I was just exploring about Dovonex and retinoids and pregnancy
because someone mentioned to me that there was a significant concern.
I have stayed off of all but mild steroid creams since trying to
conceive, but since becoming pregnant my psoriasis has cleared
significantly ... never was really bad, just knees, ankles, elbows and a
few other small patches. One
of your responses mentioned exploring this issue [P
improvement during pregnancy –Ed] and although it was an old
response I just wanted to pass this on.
Do you happen
to know which medical facility is investigating this?
Also the only
person I know who was severely afflicted was also a Type I diabetic.
Is there a higher frequency of multiple auto-immune type diseases
occurring together? Any
relationship with HLA types? We
were in medical school together and speculated about these issues, but
never took the time to explore them further.
Response: The study involving
pregnant women is being conducted now through the University of
California, Irvine. You may
email Jenny Murase ([email protected])
for more information. The
study was described in my May 2001
I wish I knew
the answer to your question about higher frequency of multiple auto-immune
type diseases occurring together. It
looks as though several genes are associated with P and several of these
have also been linked to other autoimmune conditions, but so far I’ve
not read or heard any sweeping statements about disease associations.
Misbehaving T-cells seem to be central in the P story and one may
assume these same T-cells play a role larger than making skin regenerate
faster.... But I’m told only idiots make assumptions about contemporary
So, I will keep my ears to the rail. -Ed