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Why Does Nothing Work Forever?
from Chuck D.

I'm sick and tired of "moving on to the next thing" to treat my psoriasis. I have spent over two decades boring spirals through the lists of drugs, therapies and alternatives for this condition. I've rubbed in loads of stuff, ingested new things and stopped ingesting beloved old things, regulated my sleep, soaked in variously spiced baths, injected mice residues, traveled to out-of-the-way places for miraculous sun and stinky water and popped enough pills for five lifetimes. I feel like a prospector who goes about searching for gold by starting a hole in the ground anywhere then just keeps digging forever. Nothing achieved but the act of seeking. What is it about psoriasis that makes it impossible to keep it at bay? -Chuck D.

*****

Ed's Response: What a delightful question, Chuck! (One possible answer: Entropy. But then, you could argue "Negentropy," too.)

Kidding aside, I'm sure your question is rhetorical, asked out of frustration and without anticipation of a useful answer. But it's worth asking because it expresses a perplexity that, I'd wager, has been in all of our minds at one time or another. Why IS IT so many things seem to help our lesions for awhile, then stop working? I can't place myself on the side proposing any answers to that question. On the contrary, I suspect I've asked it as many times as you.

I will offer a suspicion. I suspect nothing seems to work forever because we haven't figured out how to really "turn psoriasis off."  I hear the chorus of protestations starting up over there. Some doctors are protesting because we won't follow instructions about using our medicines; some diet promoters are also charging us with non-compliance, a great many practitioners of this and that accuse us of running out of patience and quitting the regimen rather than the regimen quitting us. And so forth.

For all the decades, centuries!, that we have been fighting psoriasis as a disease of the skin our attempts to find a cure have fallen short. Now, with our investigative focus on the immune system, we may be much closer to ending your frustrating pursuit for a permanent answer.

I personally find it interesting that consideration of the immune system as the culprit may also lead us to a reconciliation with those who have long argued diet is the best and perhaps longest lasting answer to improving psoriasis (Pagano, Connolly, Earls). Most of the more successful diets associate what we eat with what happens to our insides and associate lesions with the skin's role in elimination of toxins. The answer might not be the diets proposed or may not ONLY be the diets proposed because the proposed psoriasis reaction to toxins is not universal among people. That peculiarity may point to a difference in the immune response of psoriatics. And that difference in response may be the vein of gold old prospectors are seeking.... Correct the difference and thus be cured?

Like you, Chuck. I expect to be pondering for some time. -Ed

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