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Appetite Suppressors and Methotrexate
from Debbie W.

Hello.  I have been using methotrexate for the past 8 months with wonderful results and am up to 20mg per dose.  I realize now through your letters that the tiredness I am suffering is due to psoriatic arthritis.

Do you know if it is ok to take appetite suppressants with methotrexate as I am struggling to lose the weight which is affecting my joints?

Thanks, -Debbie

*****

Ed’s Response:  Good question.  Perhaps other readers here have had some experience with appetite suppression drugs while on MTX.  Meanwhile, ask whomever prescribed the MTX.

I would be surprised if there isn't SOME appetite suppression medicine you could use in conjunction with MTX. 

I hope the MTX will palliate your PA, too, as it did mine, returning some energy to you.  20 mg is not a huge dose.  I have taken 30 to get over a flame time, then down to 25 for maintenance.  However, my doctors said this is too much to take for any prolonged period, which is why I don’t stay on MTX for longer than 12 months.  -Ed

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