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No MTX Rebound Despite Stress
from Caroline K.

Hi again Ed. Well winter has set in here in Cape Town, South Africa and we are all freezing cold. Of course in "sunny South Africa" we don't have snow but then we don't have central heating either so it's a case of light the fire, put on the electric blanket, haul out the heaters, find those winter wooly socks, etc.

Anyway, I just thought I'd give you an update on my MTX [Methotrexate] treatment, which was going well at 25mg until I stopped it cold turkey almost 8 weeks ago. My sister passed away unexpectedly and I inherited my two nieces. So the last thing on my mind was my MTX! I just forgot to take it and when I remembered a few days later I just thought, "Oh well, I can't handle the responsibility that goes with taking MTX right now — my skin will just have to revert to it's usual psoriatic self."

Well Ed, that was 8 weeks ago and I am STILL in remission. Not a spot anywhere. It's unbelievable really as I have had huge stress to deal with. My life has changed dramatically from being a single parent of two to a single parent of four. I have not been watching my intake of "nightshade" foods and I've indulged in the odd glass of red wine or sherry here and there. But no psoriasis. I am not naive enough to believe that it's gone forever, but it's the first time in 30 years I have had a clear skin without doing anything to keep it that way!

Anyway, no doubt I'll be singing a different tune sometime soon, but for now, I'm enjoying the freedom!

Hope all my fellow flakers are doing okay out there... Keep your chins up and keep smiling! Regards, -Caroline


Previous Correspondence with Caroline K.:

Who’s Lost Hair Using Methotrexate? (April 2000) 
Tomatoes are the Culprit (May 2000) 
I Miss My Flakes. Really, I Do. (June 2000)

Ed’s Response: Good for you, Caroline! (You’re not singing the "Where-Are-My-Flakes? Blues" now, are you!) With all the horror stories about MTX rebound, it’s very good to hear you haven’t experienced any (at least not yet). But I think your accounting is very important for another reason, too. What is stress doing or not doing to your P?

Before I get too excited about what seems like a grand exception to the norm about stress exacerbating P, let’s remember the 90-day pattern. Often it takes 3 months for an apparent trigger to have a visible effect on P. As with everything else about psoriasis, I’m sure this pattern isn’t universal, but it is common and my own experience conforms to it. So it will be very important for you to report back to us sometime after 3 months from the onset of this stress-time.

And about that stress-time, please accept my and my fellow FlakeHQers condolences over the loss of your sister. Having just spent a vacation in the company of my one-and-only sissy, it is easy for me to empathize with your grief. However, my sister’s son is all grown up and I do find it hard to comprehend what virtually doubling the size of your nuclear family must be like. But that it’s stressful, I have no doubt!

Our thoughts and prayers are with you, and we expect to hear back from you soon. -Ed

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