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Helping in a Hurry
fellow flakers. This week sees
the first of a two week blitz of Dovobet. Day
two and this stuff is really working already.
Day three and it looks good, the only problem is the ointment is so
thick it’s like the old days of Dermovate mixed with paraffin which is
no fun. And the wife ain’t a
fan. Day 3 tomorrow. Looks
good so far may even be able to go swimming! -Dennis H.
Response: Glad you are
reacting to Dovobet so fast, Dennis. Hope
it lasts and you get to go swimming!
is the U.K. formularized combination of Dovonex and betamethasone
dipropionate (a.k.a. Diprolene in the U.S.).
is calcipotriene (a.k.a. calcipotriol in Europe), a topical version of
vitamin D3. According to the
National Psoriasis Foundation literature, it works best at flattening
lesions and reducing scales and less well for reducing the inflammation
that makes lesions red. Topicals
for P that don’t have long-term adverse side effects are rare, but
Dovonex is one of them. Many
derms like to try it as a first course treatment for people with mild to
moderate P because, if it works, it can be used as needed indefinitely.
dipropionate is a strong topical corticosteroid with a short list of
adverse side effects, the most common of which is thinning skin.
When it works it quells inflammation, hence reducing plaques and
the combined use of betamethasone dipropionate and Dovonex should provide
a “safer and more effective solution” for mild to moderate flakers
than use of either topical singly. Before
Dovobet, some derms were prescribing alternating daily between the two
active medicines; e.g., one in the morning, the other in the evening.
According to the manufacturer of Dovobet, simply glombing the two
unguents together and then slathering them on lesions doesn’t work,
meaning the Dovobet formulation is superior.
(Would we expect to hear anything different from the manufacturer?)
We’ve heard many more good things than bad about Dovobet here at FlakeHQ. -Ed