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Doxycycline or Sulfasalazine for PA?
from Mark St. C.

Ed, I just found your page tonight.  I have been on methotrexate for a few months.  I am having a few side effects it seems.  The dosage is low and by injection.  Do you know of anyone who has used and has had any results with doxycycline or sulfasalazine.  I have PA and was told that these antibiotics take a while but have good results without the side effects.  Any thoughts? -Mark St. C.


Ed’s response:  Using these for PA is news to me, Mark.  doxycycline is prescribed for major infections and sometimes, with other meds, to treat severe acne.  Sulfasalazine, an anti-inflammatory, is described for ulcerative colitis and sometimes for people with rheumatoid arthritis who are not responding well to aspirin or ibuprofen (all this from the PDR Family Guide to Prescription Drugs).  Also check out Sulfasalazine (Azulfidine) for P?

If these drugs do what MTX can’t, I’d surely like to learn more.  Meanwhile, Mark, you might want to ask your doctor about Enbrel for your PA. 

Let us know what happens.  -Ed

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