& Chondroitin for P-Arthritis?
from Mary Ellen Q.
A friend has recommended taking
Glucosamine & Chondroitin, an over-the-counter food supplement. She
says that it cured her arthritis and carpel tunnel syndrome and that it
has worked for other members of her family and friends with various
arthritic conditions. I have severe PA and wonder if anyone has tried it.
I have tried just about everything and don't want to take methotrexate.
-Mary Ellen Q.
Ed’s Response: It appears from
the abundance of material on these supplements that a dissertation is
possible and a PhD in order for putting it together. I recommend you go to
Ed Anderson’s "Skin Page"
and use some or all of the 28 search engines congregated there to find
references to either or both of these compounds. In just scratching the
surface, I came up with this article citation in an NIH database (read the
field labeled "Abstract (AB)"):
and Musculoskeletal and Skin Disease
Format (FM): JOURNAL ARTICLE (24).
Language(s) (LG): English.
Year Published (YR): 1999.
Audience code (AC): HEALTH PROFESSIONALS (100).
Author (AU): Walsh D'Eprio, N.
Source (SO): Patient Care. 33(12): 17-18,28. July 15, 1999.
Abstract (AB): This journal article provides health
professionals with information on the efficacy of glucosamine and
chondroitin in treating osteoarthritis (OA). A book published in 1997
touted the medical miracle of glucosamine and chondroitin supplements in
treating OA. Both conventional and alternative clinicians are taking
another look at these supplements, and the National Institutes of Health
is organizing a large, randomized trial that may provide some definitive
answers on their efficacy in treating OA. These substances, which are
naturally produced in the body, are structural components of cartilage.
The rationale for using glucosamine is that increasing the amount of
available glucosamine would improve the ratio of cartilage repair to
degradation. Studies have investigated the use of oral glucosamine versus
placebo, intramuscular glucosamine versus placebo, and oral glucosamine
versus ibuprofen. Results suggest that glucosamine may provide some
therapeutic benefits for patients with OA. Although the Arthritis
Foundation continues to advocate using the American College of
Rheumatology treatment guidelines for OA, it now offers advice to patients
considering the use of glucosamine. 9 references.
Major Descriptors (MJ): Osteoarthritis. Pain. Clinical
Trials. Medical Effectiveness. Alternative Medicine. Glucosamine.
Minor Descriptors (MN): NSAID. Cartilage. Quality of Life.
Verification/Update Date (VE): 199910.
Notes (NT): CP: Yes.
Accession Number (AN): ARS015821.
For the time being, Mary Ellen,
it appears G&C are a question mark. Many people are trying them and
reporting positive results. Keep your doc or derm informed if you plan to
try it yourself. -Ed
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